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Cyclophosphamide induced cardiotoxicity

WebJan 1, 2024 · Administration of Chemotherapeutics, especially doxorubicin (DOX) and cyclophosphamide (CPS), is commonly associated with adverse effects such as myelosuppression and cardiotoxicity. At this... WebMay 11, 2024 · Though mechanism of cyclophosphamide-induced cardiotoxicity is not completely understood, it is thought to encompass oxidative and nitrative stress. As such, this review focuses on antioxidants...

Cardiotoxicity following cyclophosphamide therapy: a case report

WebApr 7, 2024 · This present study investigated the protective effects of asperuloside (ASP) against cadmium-induced nephrocardiac toxicity. Rats were treated with 50 mg/kg of ASP for five weeks and CdCl2 (5 ... WebFeb 5, 2024 · INTRODUCTION. Cyclophosphamide (CP) is widely used in chemotherapy for malignant tumors and as an immunosuppressant for the prevention of graft rejection and treatment of chronic autoimmune diseases.1 It is one of the most effective and safe drugs used for such diseases.2 However, its detrimental side effects cannot be ignored. Thus, … db 結合 3つ https://melhorcodigo.com

Cardiotoxicity: An Unexpected Consequence of HER2-Targeted …

WebNov 1, 2024 · Cyclophosphamide (CYP)-induced cardiotoxicity is a common side effect of cancer treatment. Although it has received significant attention, the related mechanisms of CYP-induced cardiotoxicity ... WebFeb 7, 2024 · The clinical features of fatal cyclophosphamide-induced cardiotoxicity in a conditioning regimen for allogeneic hematopoietic stem cell transplantation (allo-HSCT). Ann Hematol 2016; 95(7): 1145–1150. Crossref. PubMed. Google Scholar. 35. Duléry R, Mohty R, Labopin M, et al. Early cardiac toxicity associated with post-transplant ... WebJul 18, 2015 · Cardiotoxicity and nephrotoxicity were induced in rats by a single injection of cyclophosphamide (CP; 200 mg·kg −1 , i.p.) on the first day of experimental period, whereas taurine (Tau; 200 mg ... db 精度とは

Cardioprotective Effects of Oroxylum indicum Extract Against ...

Category:Cardiotoxicity of cytotoxic drugs - PubMed

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Cyclophosphamide induced cardiotoxicity

Molecular mechanism involved in cyclop…

WebNov 8, 2024 · The Role of METTL3-Mediated N6-Methyladenosine (m6A) of JPH2 mRNA in Cyclophosphamide-Induced Cardiotoxicity The Role of METTL3-Mediated N6-Methyladenosine (m6A) of JPH2 mRNA in Cyclophosphamide-Induced Cardiotoxicity Front Cardiovasc Med. eCollection 2024. Authors WebOct 8, 2024 · Administration of Chemotherapeutics, especially doxorubicin (DOX) and cyclophosphamide (CPS), is commonly associated with adverse effects such as myelosuppression and cardiotoxicity. At this time, few approved therapeutic options are currently available for the management of chemotherapy-associated cardiotoxicity.

Cyclophosphamide induced cardiotoxicity

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WebFeb 1, 2024 · Phosphoramide is an active neoplastic agent, and acrolein is a toxic metabolite which acts on the myocardium and endothelial cells. This is the first review … WebPossible protective effects of a methanolic extract of Viscum album (VA) and quercetin (QE) against cyclophosphamide (CP) induced cardiotoxicity, urotoxicity and genotoxicity in mice were evaluated. Mice were administered orally VA (250 mg/kg/day) and QE (50 mg/kg/day) for 10 days alone or in combination with CP.

WebDec 1, 2024 · Cyclophosphamide-induced cardiotoxicity involves multiple mechanisms; oxidative stress, apoptosis, myocardial inflammation, endothelial dysfunction, calcium … WebJun 1, 2016 · PDF ABSTRAK Latar belakang: Kemoterapi sering menimbulkan efek samping berupa toksisitas hematologi. Derajat toksisitas yang timbul sering dikaitkan... Find, read and cite all the research you ...

WebCardiotoxicity that was thought to be related to CYA occurred in 1/32 (3%) of patients in Group 1 and in 13/52 (25%) patients in Group 2 (P less than 0.025). Congestive heart …

WebJun 6, 2016 · The greatest risk of cardiotoxicity from trastuzumab is in patients receiving concurrent anthracycline. 6,14 Other risk factors for trastuzumab-induced cardiotoxicity include older age, diabetes mellitus, decreased glomerular filtration rate, use of antihypertensives, and history of heart disease.

WebFeb 7, 2024 · Cyclophosphamide-induced cardiac injury is dose-dependent, with the total dose of a single course of therapy being the best indicator of toxicity, and patients receiving >150 mg/kg or 1.55 g/m 2 /d are at higher risk of cardiotoxicity ( Kusumoto et al., 2013 ). db 紐づけテーブルWebCyclophosphamide- and ifosfamide-induced cardiotoxicity is dose dependent and usually presents few days after treatment. High doses (>140 mg/kg) are considered very cardiotoxic. db 聞こえるWebFeb 21, 2024 · The clinical features of fatal cyclophosphamide-induced cardiotoxicity in a conditioning regimen for allogeneic hematopoietic stem cell transplantation (allo-HSCT). … db 結合条件とはWebNaringin prevents cyclophosphamide-induced erythrocytotoxicity in rats by abrogating oxidative stress db 結合 キーWebJul 14, 2014 · Cyclophosphamide-induced cardiotoxicity (CIC) is a well-known adverse effect and not that uncommon . Symptoms occur usually within 1 to 3 weeks, and … db 結合キーWebMar 24, 2024 · Cyclophosphamide, which can inhibit DNA replication and apoptosis, is a kind of DNA-alkylating agent for breast cancer, cyclophosphamide-induced cardiac damage is dose dependent, and mechanisms of cyclophosphamide-induced cardiotoxicity encompass oxidative and nitrative stress and protein adduct formation. db 結合 インデックスWebAbstract. A 12-year-old boy with aplastic anemia developed severe but reversible cardiac failure after treatment with 200 mg/kg cyclophosphamide (4 x 50 mg/kg on four … db 統計情報 パフォーマンス