WebAuthors confirm that the catalytic activity resides in the N-terminal two-thirds of the protease polypeptide and suggest that the C-terminal one-fifth of the protein contains a capsid targeting signal. PMID: 23688818; Subcellular Location: Virion. Protein Families: HK97 prohead protease protein family: Database Links: KEGG: vg:1262531 WebEach of these three groups will be considered in turn by focusing on the following systems: the Rec A-dependent intramolecular cleavage of the Escherichia coli SOS response protein, LexA; the intramolecular activation of the mammalian aspartic acid protease, pepsinogen; and the autocatalytic cleavage of polyproteins synthesized by picornaviruses.
Experimental evidence for proteins constituting virion components …
Webcapsid maturation protease Protease, prohead protease Sisi_4 major capsid protein capsid Sisi_6 head-to-tail connector protein Sisi_7,8,9,10 major tail protein major tail subunit Sisi_11 tail assembly chaperone Tail scaffolding protein TM4_15; 16 tape measure protein Tape Measure, tmp, tapemeasure TM4_17 WebUniProtKB reviewed (Swiss-Prot) Organism. Enterobacteria phage HK97 (Bacteriophage HK97) Amino acids. 225. Protein existence. Evidence at protein level. Annotation score. 2/5. ladda ner office 2021 professional plus
Common Evolutionary Origin of Procapsid Proteases
WebJun 26, 2024 · Phage G's decoration protein is longer than what has been reported in other phages, and we suspect the extra interaction surface area helps stabilize the capsid. We identified several additional capsid proteins, including a candidate for the prohead protease responsible for processing gp27. WebJan 1, 2005 · If proheads are assembled with a mutant form of the protease that is catalytically inactive but competent for assembly, there are roughly 50 molecules of protease per prohead, and this is presumed to be the same as the number of wild‐type proteases per prohead. WebMar 20, 2012 · The identification of 39 cleavage sites in 19 φKZ head proteins indicates cleavage of many prohead proteins forms a major morphogenetic step in φKZ head … proper sheep handling