Thbs1 expression
WebThbs1−/− monocytic cells had reduced adhesion and migratory capacity in vitro compared with wild-type counterparts. Adoptive transfer of Thbs1+/+ monocytic cells or bone marrow reconstitution rescued aneurysm development in Thbs1−/− mice. Conclusions: Web9 Mar 2024 · Also known as TSP; THBS; TSP1; TSP-1; THBS-1 Summary The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein …
Thbs1 expression
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Web27 Jul 2024 · Studies in animal models found that elevated TSP1 expression, acting in part through CD47, causes mitochondrial and metabolic dysfunction. Clinical studies established that abnormal TSP1 expression positively correlates … Web20 Feb 2024 · In patients with acute ST-segment elevation MI, the expression of TSP-1 is significantly increased ( 47 ), and the decrease of TSP-1 following percutaneous coronary intervention (PCI) is associated with major adverse cardiac events ( 48 ).
Web13 Apr 2024 · Our findings indicate that Kaiso directly represses tumor suppressor THBS1, and this is associated with increased expression of CD47 and signal regulatory protein (SIRPA). Kaiso depletion attenuated tumor formation in athymic nude mice, and this is associated with increased infiltration of M1 macrophages. Web3 Jan 2024 · Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells. …
Web1 Nov 2015 · We hypothesized that circulating THBS1 may serve as a novel biological marker of metabolic syndrome and adipose tissue inflammation associated with human … Web4 Feb 2024 · As shown in Supplementary Figure 6B, ligand Thbs1 was highly expressed by SMC-2 in the sham group, and reduced in AAA group. Thbs1 was also expressed by Maph …
WebTHBS1 is infrequently mutated in most cancers, but its expression is positively regulated by several tumor suppressor genes and negatively regulated by activated oncogenes and …
Web2 Jun 2024 · Thrombospondin-1 (THBS1) is a matrix glycoprotein that can affect fibrosis by activating TGF- β 1, which plays a key role in wound repair and tissue regeneration; … claws parentsWeb9 Mar 2024 · Also known as TSP; THBS; TSP1; TSP-1; THBS-1 Summary The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha … download tools for office 2019http://www.cancerindex.org/geneweb/THBS1.htm claws part-of-speech tagger lancs.ac.ukWeb11 Aug 2016 · Thrombospondin 1 and thrombospondin 2 (THBS1 and THBS2) share similar multifunctional domains, and are known to be antiangiogenic. However, the expression … claw sourisWeb8 Jul 2014 · THBS1 expression induces melanoma cell invasion (A) Mesenchymal- and epithelial-like melanoma cells were subjected to invasion through matrigel-coated Boyden chambers. After 48 hours cells were fixed and images of invasive cells were taken (scale bar = 500μm) or stained using THBS1 antibody in conjunction with an Alexa-488 conjugated … claws partWebTherefore, we speculate that THBS1 knockout in this study may promote the expression of the SAA1 gene, which in turn alters the adhesion of GSCs through the YAP signaling … download tools for linuxWebExpression of THBS1 is also downregulated by pregnancy recognition signals to maintain the CL during early pregnancy. This dynamic pattern of luteal expression, the extensive interactivity with other luteal factors and strong antiangiogenic and proapoptotic activities indicate that THBS1 is a major determinant of CL fate. download tools for ubuntu