2024 Tmem176a gene

Tmem176a gene

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August undefined, 2024

WebSep 24, 2024 · Lay abstract. The TMEM176A gene is often methylated in human lung cancer by addition of a methyl group to the gene promotor region. This regulates the expression of TMEM176A.We found that TMEM176A suppressed lung cancer growth both invitro and invivo by inhibiting ERK signaling. Methylation of TMEM176A sensitized H1299 and H23 … WebTmem176a Gene Detail Summary Symbol Tmem176a Name transmembrane protein 176A Synonyms 0610011I04Rik Feature Type protein coding gene IDs MGI:1913308 NCBI …

TMEM176A protein expression summary - The Human Protein Atlas

WebFeb 1, 2024 · TMEM176A and TMEM176B Are Candidate Regulators of Inhibition of Dendritic Cell Maturation and Function after Chronic Spinal Cord Injury J Neurotrauma. 2024 Feb 1 ... (PGS) software was used to limit the 54,000 gene list to only those genes up-regulated or down-regulated by 2-fold or more in SCI compared with control. Pathway … WebTMEM176A. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. grofame production

TMEM176A transmembrane protein 176A - NIH Genetic …

WebTMEM176A IMMUNE CELL CELL LINEAGES Immune cell proteome IMMUNE CELL TYPE EXPRESSION (RNA)i HPA dataseti Lineage Expression Alphabetical Immune cell type specificity: Immune cell enhanced (classical monocyte, intermediate monocyte) WebThere is a very high volume of traffic coming from your site (IP address 40.79.131.210) as of Fri Apr 14 21:17:04 2024 (California time). So that other users get a fair share of our … WebTwo MS4A-related genes, TMEM176A and TMEM176B, are located on chromosome 7. TMEM176B is broadly expressed and has been shown to be upregulated in antigen-presenting cells in a rat model of allograft tolerance [11]. Human TMEM176A was first identified from a screen of tumor-associated antigens in HCC [12]. filemaker recovery password

Tissue expression of TMEM176A - Summary - Protein Atlas

Anti-TMEM176A Antibodies Invitrogen - Thermo Fisher Scientific

WebThere are 3 isoforms (A, B, C) of this gene with variants of isoform A and C. Isoform A variant 1 has 1444 nucleotides that encode 270 amino acids. There are 17 alternatively … WebSep 26, 2024 · These data suggest that Tmem176B and Tmem176A associate to form multimers and restrain dendritic cell maturation. The Clast1 gene is ubiquitously expressed in various organs of adult mice and is required for development of cerebellar granule cells. gro family searchWebThe Genotype-Tissue Expression (GTEx) project is an ongoing effort to build a comprehensive public resource to study tissue-specific gene expression and regulation. Samples were collected from 53 non-diseased tissue sites across nearly 1000 individuals, primarily for molecular assays including WGS, WES and RNA-seq. Remaining samples are … grof afval utrecht

"WebOverexpression of TMEM176A in Capan-1 and PANC-1 cells suppressed cell proliferation, cell invasion, and migration, and induced apoptosis in pancreatic cancer cells. … " - Tmem176a gene

Tmem176a gene

Methylation of TMEM176A, a key ERK signaling regulator, …

WebJul 15, 2013 · In summary, none of the MS4A/TMEM176 genes tested was expressed at high levels in normal or in most CLL B-cells. MS4A6A and MS4A7 were expressed at low levels in most B-cell samples, however the corresponding proteins may not be positioned at the plasma membrane. WebLay abstract The TMEM176A gene is often methylated in human lung cancer by addition of a methyl group to the gene promotor region. This regulates the expression of TMEM176A. …

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WebNov 6, 2024 · TMEM176A is located in human chromosome 7q36.1, a region where there is a frequent loss of heterozygosity in human cancer [ 16, 17 ]. In our previous studies, the TMEM176A promoter was frequently methylated in human colorectal and esophageal cancers and served as a tumor suppressor in these cancers [ 18, 19 ]. WebJul 18, 2024 · Dynamic interaction between prostate cancer and the bone microenvironment is a major contributor to metastasis of prostate cancer to bone. In this study, we utilized an in vitro co-culture model of PC3 prostate cancer cells and osteoblasts followed by microarray based gene expression profiling to identify previously unrecognized prostate …

WebTMEM176A Gene Functional Associations TMEM176A has 2,939 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 63 datasets.

WebThe candidate genes TMEM176A and TMEM176AB, which are orthologous in humans, are in association with navel's trait and compose the Androgen Induced 1 cluster. ... gene introgression and contribute to include information concerning molecular markers in genetic evaluation of animal improvement programs. 1. Introduction parameters associated with ... WebTMEM176A. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC.

WebTMEM176A is part of cluster 59 Proximal enterocytes - Transmembrane transport with confidence i Confidence is the fraction of times a gene was assigned to the cluster in …

WebTMEM176A. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas … gro familyWebOfficial gene symbol, which is typically a short form of the gene name, according to HGNC. TMEM176A (HCA112, MS4B1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more. Transporters. Number of transcriptsi. Number of protein-coding transcripts from the gene as defined by Ensembl. gro fairfieldWebThe expression and transcription of TMEM176A (transmembrane protein 176A) gene is altered in multiple cancers. It is highly up-regulated in lung carcinoma cells. This protein has potential as a marker for breast carcinoma, lymphoma and melanoma and hepatocellular carcinoma (HCC). grofan.comWebTMEM176A: Mouse gene name: Tmem176a Human gene description i. Transmembrane protein 176A: Predicted location i Membrane: Mouse gene: ENSMUSG00000023367 (version 103) Pig gene: ENSSSCG00000016443 (version 103) Antibodies in assay i. No antibodies in assay HUMAN PROTEIN ATLAS INFORMATION; Tissue specificity i. Tissue enhanced … gro family services precreen form page 2WebMar 21, 2024 · Protein details for TMEM176A Gene (UniProtKB/Swiss-Prot) Protein Symbol: Q96HP8-T176A_HUMAN Recommended name: Transmembrane protein 176A Protein … grof andrassyWebNov 6, 2024 · TMEM176A expression induced cell apoptosis; inhibited cell proliferation, migration, and invasion; suppressed human HCC cell xenograft growth in mice; and inhibited ERK signaling in HCC cells. filemaker relationships tutorialWebJul 4, 2016 · TMEM176A/B, OLR1 and FOSB were upregulated in nvAMD, while FAIM3 and MS4A1 were downregulated). ... Gene lists were pulled from MSigDB to determine enrichment of genes in 49 predetermined lists ... filemaker relationships